A number of location shots were filmed in the real Pixley. The exact location of Hooterville is never mentioned on Petticoat Junction or Green Acres. Clues given to the location of Hooterville often conflict with each other, but nearby mentions of towns and counties place it in Southwest Missouri.

Six actresses played Petticoat Junction sisters.

Henning added that despite the great loss everyone involved in “Petticoat Junction” endured, the adoration among the cast still lives on. “After our show was off the air, every now and then I'd see somebody from our crew on another set, and it would be like old times,” she said. “We were all a family.”

Petticoat Junction (1963–1970) is based on the Burris Hotel, a real hotel that existed in Eldon, Missouri. Paul Henning, the producer and creator of the show, was married to the granddaughter of the owner of the hotel and often visited. The Burris hotel became the "Shady Rest Hotel" on Petticoat Junction.